1. Skin Rejuvenation & Anti-Aging

One of the strongest effects.

• Increases collagen production

• Improves elastin, glycosaminoglycans, and skin thickness

• Reduces fine lines & wrinkles

• Tightens and firms skin

• Improves texture and hydration

• Helps with hyperpigmentation

GHK-Cu is widely used in anti-aging serums for this reason.

2. Wound Healing & Tissue Repair

GHK-Cu speeds tissue repair by:

• Stimulating new blood vessel formation

• Reducing inflammation

• Enhancing fibroblast activity

• Improving skin regeneration

It is used for:

• burns

• scars

• ulcers

• post-procedure healing

3. Anti-Inflammatory Effects

GHK-Cu suppresses certain inflammatory cytokines and helps calm irritated or damaged tissue.

4. Hair Growth & Hair Follicle Strength

GHK-Cu may:

• improve scalp circulation

• reduce follicle inflammation

• extend anagen (growth phase)

It is frequently used in hair-growth formulations.

5. Antioxidant & Anti-Glycation Benefits

GHK-Cu protects cells from oxidative stress and prevents glycation-related skin aging (a process that makes collagen stiff and weak).

6. May Support Nerve & Organ Repair (Early Research)

Preclinical studies show possible benefits in:

• nerve regeneration

• lung repair

• liver protection

These areas are still being researched — not established treatments.

7. Improves Overall Cell Signaling

GHK-Cu activates multiple gene pathways involved in:

• repair

• regeneration

• anti-inflammation

• detoxification

It behaves like a “reset” signal for aging or damaged cells.

GHK-Cu is a signal peptide.
It tells your cells to repair, regenerate, and reduce inflammation.

It attaches to copper ions and delivers them into cells — triggering healing and collagen-building pathways.

Stimulates Collagen & Skin Matrix Repair

activates fibroblasts to produce:

• Collagen I & III

• Elastin

• Glycosaminoglycans (like hyaluronic acid)

• Proteoglycans

This improves:

• wrinkles

• skin texture

• firmness

• hydration

Boosts Wound Healing

promotes healing by:

• attracting immune cells to the injury site

• stimulating new blood vessel formation (angiogenesis)

• improving cell migration

• reducing inflammation in damaged tissue

This is why it’s used for:

• scars

• burns

• post-procedure healing

Acts as a Potent Anti-Inflammatory Molecule

downregulates inflammatory genes and upregulates repair genes.
It lowers cytokines like:

• TNF-α

• IL-6

This creates a healthier environment for skin and tissue regeneration.

Strong Antioxidant & Protects Cells

• neutralizes free radicals

• protects cells from oxidative stress

• helps DNA repair

• reduces glycation (which makes collagen stiff and aged)

This slows visible signs of aging.

Delivers Copper Into Cells (Copper Transport Function)

essential for:

• collagen production

• antioxidant enzymes (like SOD)

• angiogenesis

But free copper is toxic.
GHK safely binds and transports copper exactly where it’s needed.

Promotes Hair Growth

stimulates hair follicles by:

• increasing scalp blood flow

• reducing follicular inflammation

• extending the anagen (growth) phase

• increasing size of hair follicles

This is why it's used in hair serums and scalp treatments.

Regulates Gene Expression

One of its most important actions:

GHK-Cu switches on hundreds of genes related to:

• repair

• regeneration

• anti-inflammation

• cell survival

…and switches off genes related to:

• inflammation

• tissue breakdown

• oxidative damage

This “youthful gene reset” effect is a major reason it’s popular in anti-aging science.

Works by:

✔ repairing skin matrix (collagen, elastin)

✔ reducing inflammation

✔ accelerating healing

✔ delivering copper safely into cells

✔ protecting cells from oxidative stress

✔ improving blood flow & tissue oxygenation

✔ activating gene pathways for repair and regeneration

✔ strengthening hair follicles 

• Bruising or injection-site pain

• Lumps or nodules

If injected too superficially or in the same area repeatedly.

• Systemic copper increase (rare)

High or frequent doses may raise copper levels, which could cause:

• nausea

• metallic taste

• headache

• fatigue

• digestive discomfort

• Hypotension or dizziness

Very uncommon, but possible if blood vessel dilation occurs.

• Allergic reactions

Symptoms may include:

• swelling

• hives

• rapid heartbeat

• breathing trouble (very rare)

Any severe symptoms require immediate medical attention.