CJC-1295 (No Dac) (10mg)

Quick Start Highlight

CJC-1295 No DAC is the unmodified version of the CJC-1295 peptide—meaning it does not include the Drug Affinity Complex (DAC) that prolongs half-life.

Without the DAC attachment, CJC-1295 No DAC acts as a short-acting GHRH analog, producing a pulsatile release of growth hormone that more closely mimics the body’s natural GH secretion patterns.

However, because it is metabolized more rapidly, CJC-1295 No DAC has a much shorter half-life—approximately 30 minutes to 2 hours—and is typically administered once or twice per day to achieve consistent effects.

Key characteristics of CJC-1295 No DAC:

• Short half-life: ~30 minutes to 2 hours

• Injection frequency: Once or twice daily

• GH release pattern: More pulsatile and physiologic (spikes, not constant elevation)

• Use cases: Anti-aging, skin rejuvenation, recovery, joint/tissue repair, general GH optimization

Because of its more natural release profile, CJC-1295 No DAC is often favored by users looking to preserve normal GH feedback loops and avoid the potential downregulation of GH receptors that can occur with constant GH elevation.

Benefits of CJC-1295 No DAC

CJC-1295 No DAC offers a different set of advantages—especially for users who want to mimic the body’s natural GH pulse and prioritize recovery, skin health, and anti-aging outcomes.

Physiologic GH Pulse

Unlike the sustained elevation produced by CJC-1295 DAC, No DAC stimulates short bursts of GH release, closely resembling the body’s natural ultradian rhythm of GH secretion.

This pulsatile release is important for:

• Maintaining GH receptor sensitivity

• Supporting normal feedback loops

• Promoting healthier long-term hormone balance

Anti-Aging and Skin Rejuvenation

CJC-1295 No DAC is frequently used in anti-aging protocols because the pulsatile GH stimulation:

• Enhances collagen synthesis → improving skin elasticity and appearance

• Supports fat metabolism → reducing visceral and subcutaneous fat

• Improves sleep quality → deepening slow-wave sleep where natural GH pulses occur

Recovery and Joint Support

Though less commonly discussed, CJC-1295 No DAC can also be used in injury recovery stacks alongside BPC-157 and TB500.

By supporting:

• Pulsatile IGF-1 release

• Improved sleep quality

• Enhanced collagen turnover

No DAC can complement recovery protocols—especially for those concerned about receptor desensitization with DAC.

More Control Over Dosing

Since CJC-1295 No DAC is short-acting, users can time their injections around training or before bed to maximize specific outcomes:

• Pre-bed dosing to enhance GH pulses during slow-wave sleep

• Post-workout dosing to support muscle recovery and tissue repair

Conclusion for No DAC users: If your goals include anti-aging, skin improvement, general wellness, or optimized recovery with minimal risk of receptor desensitization, CJC-1295 No DAC offers a more physiologic and flexible option.

How Does CJC-1295 No DAC Work?

CJC-1295 No DAC works within a shorter time frame. It produces a brief pulse of growth hormone after each injection—mimicking the body's natural ultradian GH rhythm (several pulses of GH released throughout the day and night). Because it does not remain in circulation for extended periods, it allows the body’s negative feedback loops to remain intact, helping preserve GH receptor sensitivity. 

It is favored when a more natural GH rhythm is desired—often in anti-aging or recovery applications where maintaining receptor sensitivity is important.

Potential Side Effects

Flushing / warmth

• A common reaction after injection.

Headaches

• GH and GHRH peptides can increase intracranial pressure slightly.

Fatigue or sleepiness

• GH pulses often increase deep sleep pressure.

• Nausea or stomach discomfort

• Lightheadedness / dizziness

• Irritability or mood changes

• Usually mild and temporary.

Dosing & Reconstitution Guide

Educational guide for reconstitution and weekly dosing